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Valproic acid sodium salt
CAS No. 1069-66-5
Valproic acid sodium salt ( Sodium Valproate )
Catalog No. M10288 CAS No. 1069-66-5
A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 38 | In Stock |
|
| 1G | 45 | In Stock |
|
Biological Information
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Product NameValproic acid sodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionA HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
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DescriptionA HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2; induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients; reduces tumor growth and metastasis formation in animal model.Migraine Approved
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SynonymsSodium Valproate
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorGABAR;HDAC2;HDAC9
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Research AreaNeurological Disease
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IndicationMigraine
Chemical Information
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CAS Number1069-66-5
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Formula Weight166.19
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Molecular FormulaC8H15NaO2
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Purity>98% (HPLC)
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SolubilityH2O: ≥ 48 mg/mL
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SMILESCCCC(CCC)C([O-])=O.[Na+]
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Chemical NamePentanoic acid, 2-propyl-, sodium salt (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Krmer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
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