Valproic acid sodium salt

CAS No. 1069-66-5

Valproic acid sodium salt ( Sodium Valproate )

Catalog No. M10288 CAS No. 1069-66-5

A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 38 In Stock
1G 45 In Stock

Biological Information

  • Product Name
    Valproic acid sodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
  • Description
    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2; induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients; reduces tumor growth and metastasis formation in animal model.Migraine Approved
  • Synonyms
    Sodium Valproate
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    GABAR;HDAC2;HDAC9
  • Research Area
    Neurological Disease
  • Indication
    Migraine

Chemical Information

  • CAS Number
    1069-66-5
  • Formula Weight
    166.19
  • Molecular Formula
    C8H15NaO2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: ≥ 48 mg/mL
  • SMILES
    CCCC(CCC)C([O-])=O.[Na+]
  • Chemical Name
    Pentanoic acid, 2-propyl-, sodium salt (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Krmer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
molnova catalog
related products
  • ACY-775

    ACY-775 (ACY775) is a potent and specific HDAC6 inhibitor (IC50=7.5 nM) with improved brain bioavailability.

  • MC-1568

    A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.

  • Belinostat

    A potent HDAC inhibitor with IC50 of 27 nM.